p-hydroxyphenylacetic acid
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Name: p-hydroxyphenylacetic acid
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Description: 4-hydroxyphenylacetic acid is a monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 4-hydroxyphenyl group. It has a role as a plant metabolite, a fungal...
Overview of age-variations
| Age group comparisons | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| 8369101 | Age 33.8 ± 9.1, Gender ⚥ | 21.5 (ng/ml) | HPLC-ED | cerebrospinal fluid |
| 8369101 | Age 56.8 ± 4.3, Gender ⚥ | 33.1 (ng/ml) | HPLC-ED | cerebrospinal fluid |
| 8369101 | Age 68.2 ± 1.8, Gender ⚥ | 30.3 (ng/ml) | HPLC-ED | cerebrospinal fluid |
| Linear regression | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| log2 ratio/log2(FC) | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
Summary
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Synonym:4-hydroxyphenylacetic acid
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Chemical Formula:C8H8O3
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Exact Mass g/mol:152.0000000
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Systematic name:2-(4-hydroxyphenyl)acetic acid
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SMILES:C1=CC(=CC=C1CC(=O)O)O
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InChI:InChI=1S/C8H8O3/c9-7-3-1-6(2-4-7)5-8(10)11/h1-4,9H,5H2,(H,10,11)
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InChI Key:XQXPVVBIMDBYFF-UHFFFAOYSA-N
Related resources
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Literature sources:
- Tohgi H et al., The effect of age on concentrations of monoamines, amino acids, and their related substances in the cerebrospinal fluid., Journal of neural transmission. Parkinson's disease and dementia section, 215-26, 1993
Pathway info P = product of S = substrate of
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Tyrosine metabolism S P other metabolites from MetaboAge4-hydroxyphenylacetate Norepinephrine Vanillylmandelic acid (VMA) fumaric acid homovanillate (HVA) normetanephrine pyruvate vanillylmandelate (VMA)
Metabolic pathways other metabolites from MetaboAge1,7-dimethyluric acid 1-methylnicotinamide 1-methylxanthine 11,12-dihydroxy-eicosatrienoic acid 4-acetamidobutanoate 4-hydroxybenzoic acid 4-hydroxyphenylacetate 4-methyl-2-oxopentanoate D-glucose D-glucuronate D-mannitol D-mannose D-ribose D-sorbitol D-xylose Dihydroxymandelic acid (DHMA) L-citrulline L-threonine N-acetylneuraminate N-acetylornithine N-methyl-4-pyridone-3-carboxamide N6-acetyl-lysine NAD+ NADP+ Norepinephrine UDP-acetyl-glucosamine Vanillylmandelic acid (VMA) acetone acetylphenylalanine alpha-tocopherol androstenedione arachidonic acid arginine beta-hydroxyisovalerate beta-tocopherol betaine caffeine campesterol carnosine cholesterol choline choline phosphate citric acid cortisone creatine creatinine dehydroepiandrosterone dimethyl sulfone dimethylamine dimethylglycine fumaric acid gamma-tocopherol glutarate glutathione glycine guanidinoacetic acid gulonic acid homovanillate (HVA) hypoxanthine inosine inositol 1-phosphate kynurenic acid leukotriene E4 linoleic acid myo-inositol niacinamide nicotinic acid normetanephrine oxalic acid paraxanthine phenylglyoxylic acid pregnelone propylene glycol pyridoxic acid pyruvate quinic acid scyllo-inositol sphingosine 1-phosphate taurine theobromine trans-4-hydroxyproline trimethylamine N-oxide tryptamine urate urea uric acid uridine vanillylmandelate (VMA) xanthine
Metabolite sources and localization
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Metabolite location:Human organism, Body part, Extracellular, Human body biofluids, Biofluid tissues, Blood, Cerebrospinal fluid, Saliva, Urine, Organ, Kidney, Prostate, Skin, Skin tissue, Epidermis, Tissue, Cellular (general class), Subcellular, Cytoplasm, Excreta material, Feces
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Metabolite source:Homo sapiens, endogenous metabolite