L-threonine
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Name: L-threonine
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Description: An essential amino acid occurring naturally in the L-form, which is the active form. It is found in eggs, milk, gelatin, and other proteins. (MeSH:D013912)
Overview of age-variations
| Age group comparisons | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| 18384253 | Age 24.5 ± 3, Gender ⚥ | 0.82 (mean value of the compound area) | LC-MS; GC-MS | plasma |
| 18384253 | Age 40.8 ± 5.6, Gender ⚥ | 1.04 (mean value of the compound area) | LC-MS; GC-MS | plasma |
| 18384253 | Age 55.6 ± 3.7, Gender ⚥ | 1.28 (mean value of the compound area) | LC-MS; GC-MS | plasma |
| 12768504 | Age 32.6 ± 4.4 , Gender ♀ | 200.0 (μmol/l) | LC | blood |
| 12768504 | Age 48 ± 4.3, Gender ♀ | 142.0 (μmol/l) | LC | blood |
| 12768504 | Age 74.7 ± 10, Gender ♀ | 134.0 (μmol/l) | LC | blood |
| 12768504 | Age 33.3 ± 3.8, Gender ♂ | 137.0 (μmol/l) | LC | blood |
| 12768504 | Age 48.4 ± 6, Gender ♂ | 148.0 (μmol/l) | LC | blood |
| 12768504 | Age 75.9 ± 9.3, Gender ♂ | 128.0 (μmol/l) | LC | blood |
| Linear regression | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| log2 ratio/log2(FC) | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
Summary
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Synonym:Thr
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Chemical Formula:C4H9NO3
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Systematic name:(2S,3R)-2-amino-3-hydroxybutanoic acid
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SMILES:C[C@H]([C@@H](C(=O)O)N)O
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InChI:InChI=1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1
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InChI Key:AYFVYJQAPQTCCC-GBXIJSLDSA-N
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CAS number:7013-32-3
Related resources
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Literature sources:
- Lawton KA et al., Analysis of the adult human plasma metabolome., Pharmacogenomics, 383-97, 2008
- Pitkänen HT et al., Serum amino acid concentrations in aging men and women., Amino acids, 413-21, 2003
Pathway info P = product of S = substrate of
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Metabolic pathways other metabolites from MetaboAge1,7-dimethyluric acid 1-methylnicotinamide 1-methylxanthine 11,12-dihydroxy-eicosatrienoic acid 4-acetamidobutanoate 4-hydroxybenzoic acid 4-hydroxyphenylacetate 4-methyl-2-oxopentanoate D-glucose D-glucuronate D-mannitol D-mannose D-ribose D-sorbitol D-xylose Dihydroxymandelic acid (DHMA) L-citrulline N-acetylneuraminate N-acetylornithine N-methyl-4-pyridone-3-carboxamide N6-acetyl-lysine NAD+ NADP+ Norepinephrine UDP-acetyl-glucosamine Vanillylmandelic acid (VMA) acetone acetylphenylalanine alpha-tocopherol androstenedione arachidonic acid arginine beta-hydroxyisovalerate beta-tocopherol betaine caffeine campesterol carnosine cholesterol choline choline phosphate citric acid cortisone creatine creatinine dehydroepiandrosterone dimethyl sulfone dimethylamine dimethylglycine fumaric acid gamma-tocopherol glutarate glutathione glycine guanidinoacetic acid gulonic acid homovanillate (HVA) hypoxanthine inosine inositol 1-phosphate kynurenic acid leukotriene E4 linoleic acid myo-inositol niacinamide nicotinic acid normetanephrine oxalic acid p-hydroxyphenylacetic acid paraxanthine phenylglyoxylic acid pregnelone propylene glycol pyridoxic acid pyruvate quinic acid scyllo-inositol sphingosine 1-phosphate taurine theobromine trans-4-hydroxyproline trimethylamine N-oxide tryptamine urate urea uric acid uridine vanillylmandelate (VMA) xanthine
Biosynthesis of amino acids S P other metabolites from MetaboAge4-methyl-2-oxopentanoate L-citrulline N-acetylornithine arginine citrate citric acid glycine pyruvate
Metabolite sources and localization
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Metabolite location:Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Plasma, Tissue
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Metabolite source:Homo sapiens, exogenous metabolite